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Quantile shrinkage normalization

Source: R/YARN.R
qsmooth.Rd

This function was modified from github user kokrah.

Usage

qsmooth(
  obj,
  groups,
  norm.factors = NULL,
  plot = FALSE,
  window = 0.05,
  log = TRUE
)

Source

Kwame Okrah's qsmooth R package

Arguments

obj

for counts use log2(raw counts + 1)), for MA use log2(raw intensities)

groups

groups to which samples belong (character vector)

norm.factors

scaling normalization factors

plot

plot weights? (default=FALSE)

window

window size for running median (a fraction of the number of rows of exprs)

log

Whether or not the data should be log transformed before normalization, TRUE = YES.

Value

Normalized expression

Examples

data(skin)
head(netZooR:::qsmooth(skin,groups=pData(skin)$SMTSD))